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"Endocrinology and Diabetes (Specialty Certificate Examination)", also known as SEND exam, is a MRCPUK Certification. With the complete collection of questions and answers, ExamcollectionPass has assembled to take you through 200 Q&As to your SEND Exam preparation. In the SEND exam resources, you will cover every field and category in MRCPUK Certification Certification helping to ready you for your successful MRCPUK Certification.
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1. A 17-year-old Caucasian girl presented with primary amenorrhea.
On examination, her body mass index was 21 kg/m2 (18-25). Her body habitus was normal and she had appropriate breast development. There was no hirsutism or acne.
Investigations:
serum oestradiol<180 pmol/L (200-400) serum testosterone31.7 nmol/L (0.5-3.0) serum follicle-stimulating hormone4.0 U/L (2.5-10.0) serum luteinising hormone6.0 U/L (2.5-10.0)
What is the most likely diagnosis?
A) adrenocortical carcinoma
B) androgen-secreting ovarian tumour
C) polycystic ovary syndrome
D) ovarian hyperthecosis
E) complete androgen insensitivity syndrome
2. A 42-year-old policewoman presented with thirst, polyuria and tiredness of 3 months' duration. She gave a family history of thyrotoxicosis.
On examination, her pulse was 108 beats per minute and her blood pressure was 150/70 mmHg. She had a fine tremor and diffuse thyroid enlargement. She also had mild proptosis.
Investigations:
haemoglobin146 g/L (115-165)
platelet count164 ? 109/L (150-400)
serum sodium143 mmol/L (137-144)
serum creatinine135 umol/L (60-110)
serum corrected calcium3.60 mmol/L (2.20-2.60)
serum thyroid-stimulating hormone<0.02 mU/L (0.4-5.0)
serum free T431.9 pmol/L (10.0-22.0)
serum free T315.6 pmol/L (3.0-7.0)
What is the most appropriate next investigation?
A) isotope bone scan
B) plasma parathyroid hormone
C) fine-needle aspiration of thyroid
D) 24-h urinary calcium
E) serum phosphate
3. A 67-year-old woman with type 2 diabetes mellitus presented to the foot clinic with an ulcer at the plantar aspect of her fifth left toe. The ulcer probed to bone but there were no signs of inflammation. There had been a little improvement during 6 weeks of podiatric treatment, but there was some concern about possible osteomyelitis. An X-ray of toe 4 weeks previously had been normal.
What is the most appropriate next investigation?
A) triple phase isotope bone scan
B) CT scan of foot
C) plain X-ray of foot
D) MR scan of foot
E) white cell labelled scan
4. A 16-year-old girl presented with primary amenorrhoea. In early childhood she had undergone an inguinal herniorrhaphy. She had no other medical history of note. There was a family history of infertility affecting a maternal aunt.
On examination, she had adult breast development but no pubic or axillary hair. Examination was otherwise normal.
What test is most likely to aid diagnosis?
A) plasma gonadotropins
B) ovarian antibody titres
C) blood karyotype
D) ultrasound scan of pelvis
E) MR scan of pituitary and olfactory bulbs
5. A 56-year-old man was referred to the diabetes clinic for conversion to insulin. He was taking metformin 1 g three times daily, gliclazide 160 mg twice daily and pioglitazone 45 mg daily. He drank no alcohol.
On examination, his body mass index was 41 kg/m2 (18-25). Abdominal examination showed a 2-cm, smooth, non-tender liver edge.
Which liver function test is the best marker of non-alcoholic fatty liver disease in type 2 diabetes mellitus?
A) alanine aminotransferase
B) aspartate aminotransferase
C) alkaline phosphatase
D) bilirubin
E) gamma glutamyl transferase
Solutions:
| Question # 1 Answer: E | Question # 2 Answer: B | Question # 3 Answer: C | Question # 4 Answer: C | Question # 5 Answer: A |
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