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American Society of Microbiology ABMM Exam Syllabus Topics:
| Section | Objectives |
|---|---|
| Clinical Microbiology | - Virology
|
| Infectious Disease Principles | - Epidemiology
|
| Laboratory Management & Quality Systems | - Quality assurance and quality control
|
| Laboratory Operations | - Instrumentation and methodologies
|
American Society of Microbiology ABMM Sample Questions:
A research laboratory is investigating the mechanisms of antiviral drug resistance. They are studying a herpes simplex virus strain that has developed resistance to acyclovir. The MOST common mechanism of acyclovir resistance in HSV involves mutations in the gene encoding:
- A. Viral thymidine kinase
- B. Viral glycoprotein D
- C. Viral DNA polymerase
- D. Viral protease
Correct Answer: A 🗳️
An immunocompromised patient develops a disseminated fungal infection. Blood cultures are consistently negative. However, a serum beta-D-glucan assay is markedly elevated. Tissue biopsy reveals the presence of hyaline, septate hyphae with dichotomous branching. The MOST likely causative organism is:
- A. Cryptococcus neoformans
- B. Mucor species
- C. Aspergillus fumigatus
- D. Rhizopus species
Correct Answer: C 🗳️
A previously healthy 28-year-old female develops a severe, watery diarrhea after attending a picnic where she consumed potato salad that had been left unrefrigerated for several hours. Stool culture reveals numerous Gram-positive bacilli. Further biochemical testing shows the organism is beta-hemolytic on blood agar and produces a heat-stable enterotoxin. The MOST likely causative agent is:
- A. Vibrio cholerae
- B. Staphylococcus aureus
- C. Clostridium difficile
- D. Bacillus cereus
Correct Answer: D 🗳️
A clinical microbiology laboratory encounters a Gram-negative bacillus isolated from a bloodstream infection. The isolate exhibits resistance to multiple antibiotics, including carbapenems. Further phenotypic testing reveals the production of a metallo-beta-lactamase (MBL). Which of the following antibiotic combinations might still retain activity against this isolate?
- A. Ceftazidime-avibactam
- B. Aztreonam
- C. Piperacillin-tazobactam
- D. Aztreonam-avibactam
Correct Answer: B 🗳️
A patient develops a febrile illness with a diffuse petechial rash after a camping trip. Serological testing reveals a four-fold rise in antibody titer to Rickettsia rickettsii. The vector responsible for transmitting this organism is a:
- A. Tick
- B. Louse
- C. Flea
- D. Mosquito
Correct Answer: A 🗳️
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