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ASCP ASCP-MLT Exam Syllabus Topics:

ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Primary- Target glands (such as thymus, thyroid, parathyroid, etc.)
Secondary- Pituitary gland
Tertiary- Hypothalamus
Match the type of endocrine dysfunction with the appropriate organ:
1. Target gland
2. Pituitary gland
3. Hypothalamus

A) Primary
B) Secondary
C) Tertiary

2. There are many causes of CSF lymphocytosis. Lymphocytosis is seen in viral, fungal, and tuberculous infections, although a predominance of neutrophils may be present in the early stages of these infections.
Lumbar puncture to obtain CSF samples is often contraindicated in those with a suspected brain abscess.
CSF lymphocytosis is associated with all of the following except:

A) Chronic fungal meningitis
B) Viral meningitis
C) Chronic tuberculous meningitis
D) Cerebral abscess

3. No HLA matching is performed for corneal tissue transplants as the cornea occupies a privileged site not usually seen by the immune system. This term has been coined "immune privileged".
Corneal tissue may be transplanted successfully from one patient to another because:

A) Anti-corneal antibodies are easily suppressed
B) The cornea has the same DNA in everyone.
C) The cornea is non-antigenic
D) Corneal antigens do not activate T cells
E) The cornea occupies a privileged site not usually seen by the immune system

4. In radioimmunassay, a fixed concentration of labeled antigen is incubated with a constant amount of antiserum such that the concentration of antigen binding sites on the antibody is limiting. If unlabeled antigen is added to this system, there is competition between labeled antigen and unlabeled antigen for the limited and constant number of binding sites on the antibody, and thus the amount of labeled antigen bound to antibody will decrease as the concentration of unlabeled antigen increases.
Which of the following choices is correct when describing the principles of competitive radioimmunoassay procedures?

A) antibody will react directly with radioactive labeled immunoglobulin
B) antibody will react preferentially with the unlabeled antigen
C) antibody will react equally with labeled and unlabeled antigen
D) antibody will react with labeled antigen only
E) antibody will react preferentially with the labeled antigen

5. A positive DAT is consistent with a diagnosis of hemolytic disease of the newborn. A hemoglobin performed on the cord blood serves as an indicator of the severity of the disease.
In order to detect the presence of antibodies fixed on the RBC's of newborns one should:

A) Look for agglutination in a mixture of mother's serum and baby's cells
B) Test the baby's cells with typing antiserum
C) Perform an indirect antiglobulin test (IAT) on the cord blood
D) Perform a direct antiglobulin test (DAT) on the cord blood

Solutions: